The TPA1286 family lets designers set any gain from 1 to 1,000 with a single external resistor — a capability that drives its adoption in precision sensing applications. This article provides an actionable, datasheet-focused analysis of CMRR and gain behavior for designers working with TPA1286U-VS1R, plus practical measurement steps and design guidance to validate real-world performance.
The TPA1286U-VS1R is a zero-drift instrumentation amplifier with single-resistor gain setting (gain range 1\u20131000), rail-to-rail output capability, and low input bias current suitable for precision bridge and low-frequency sensor front ends. Its architecture targets low offset drift and long-term stability, making it useful for strain gauges, thermistor bridges, and other small-differential-signal sensors that coexist with large common-mode voltages.
When extracting datasheet numbers, capture typical and worst-case values and the measurement conditions (supply, temperature). Pull offset, bias current, supply current, slew rate, common-mode range, output swing, and recommended Rg range. Below is a compact reference table for quick comparison; verify exact limits and conditions in the official datasheet for production decisions.
| Spec | Typical | Max | Unit |
|---|---|---|---|
| Input offset voltage | ~25 | 100 | µV |
| Input bias current | 10 | nA | |
| Supply current | ~2.5 | 4 | mA |
| Slew rate | 1 | 5 | V/µs |
| Common-mode input range | Rail ±0.1 | — | V |
| Output swing | Rail ±20 | — | mV |
| Recommended Rg range | 100 | 100k | Ω |
CMRR quantifies rejection of common-mode signals and is expressed in dB: CMRR(dB) = 20·log10(Ad/Ac), where Ad is differential gain and Ac is common-mode gain. High CMRR ensures a small differential input (microvolts to millivolts) is not overwhelmed by large common-mode voltages from sensor offsets or EMI. For sensor accuracy, translate CMRR into an equivalent input error at expected common-mode levels to set design margins.
Datasheets typically show DC CMRR and CMRR vs frequency. Expect the highest CMRR at DC with gradual degradation at higher frequency — the −3 dB point indicates where rejection falls notably. For the TPA1286 family, extract DC CMRR and the frequency at which CMRR drops by 3\u20135 dB; annotate curves at the gains you plan to use to verify acceptance across your signal band.
The datasheet gives a single-resistor formula of the form Gain = 1 + K/Rg, where K is an internal constant specified therein. Algebraically, Rg = K / (Gain - 1). Using a common example constant K = 100kΩ for worked examples (verify K in the datasheet):
| Target gain | Example Rg (K=100kΩ) | Expected impact |
|---|---|---|
| 1 | Open (∞) | Max bandwidth, lowest noise contribution |
| 10 | 11.1kΩ | Moderate BW reduction, improved signal amplitude |
| 100 | 1.01kΩ | Reduced BW, higher input-referred noise |
| 1000 | 100Ω | Significant BW limit, layout-sensitive CMRR |
Choose precision Rg (0.1\u20131% depending on accuracy needs). Lower Rg values increase current and can introduce resistor noise; balance tolerance vs noise when specifying part values.
Higher gain typically reduces closed-loop bandwidth and can increase input-referred noise after scaling; CMRR can become more sensitive to mismatch and layout at very high gains. Consult gain-dependent curves in the datasheet (noise vs gain, bandwidth vs gain) and follow layout practices: short, matched input traces, star grounding, and local decoupling to preserve both CMRR and noise performance.
A robust setup includes: precision function generator(s) or differential source, low-noise differential amplifier or buffer for stimulus, calibrated precision Rg resistors, high-resolution oscilloscope with differential probe, spectrum analyzer or FFT-capable DAQ, and a stable power supply. Use shielded connections and a driven guard if measuring microvolt-level offsets to avoid probe loading and leakage.
Step 1: Configure the amplifier with the chosen Rg and apply a small differential input (e.g., 1 mVpp); measure output amplitude to compute Ad = Vout/Vin. Step 2: Apply a known common-mode voltage (Vc) with zero differential input; measure Vout to compute Ac = Vout/Vc, then CMRR(dB)=20·log10(Ad/Ac). Step 3: Repeat across frequency to produce CMRR vs frequency. Watch for probe loading, ground loops, and source imbalance; mitigate with buffering and symmetry. Compare measured curves to datasheet typical/min specs to accept or iterate design changes.
Low-frequency: bridge strain gauge. Choose moderate gain (10\u2013100) to bring microvolt-level bridge signals into ADC range, prioritize DC CMRR and thermal stability, use low-drift precision Rg, and enforce symmetrical routing. High-frequency: vibrational sensor or biopotential frontend. Favor lower gain at the amplifier stage and use subsequent filtering/amplification to meet bandwidth; verify CMRR across the instrument bandwidth and control input protection to prevent slew-rate issues.
The TPA1286U-VS1R delivers flexible single-resistor gain and low-drift performance ideal for precision sensors; designers must read CMRR curves and gain-dependent specs to predict real-world behavior. Follow the calculation steps for Rg, validate gain and CMRR on the bench, and apply the layout checklist to preserve performance before committing to a PCB spin. Download the TPA1286 datasheet and run the provided bench checklist before committing to a PCB spin.




